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Prospective molecular identification of ovarian cancer patients benefiting from PARP inhibitor (PARPi, rucaparib) maintenance therapy – reaching beyond germline BRCA mutations

Authors: E Swisher, I McNeish, RL Coleman, JD Brenton, SH Kaufmann, A Allen, M Rapon...
E-pub date: 1 Aug 2014
Journal name: CANCER RESEARCH

Immunohistochemistry predicts presence and type of TP53 mutation in high-grade serous carcinoma

Authors: M Koebel, A Piskorz, S Liu, JD Brenton
E-pub date: 1 Aug 2014
Journal name: CANCER RESEARCH

ARIEL 2/3: An integrated clinical trial program to assess activity of rucaparib in ovarian cancer and to identify tumor molecular characteristics predictive of response.

Authors: EM Swisher, IA McNeish, RL Coleman, J Brenton, SH Kaufmann, AR Allen, M Rap...
E-pub date: 1 Aug 2014
Journal name: JOURNAL OF CLINICAL ONCOLOGY

A national platform for molecular diagnostics: Results of the Cancer Research UK Stratified Medicine Programme

Authors: E Shaw, R Butler, DG de Castro, M Griffiths, A Hanby, J Hair, F Rae, J Roga...
E-pub date: 1 Aug 2014
Journal name: JOURNAL OF CLINICAL ONCOLOGY

ICON8: An international randomized trial comparing two dose dense regimens, 3-weekly carboplatin plus weekly paclitaxel (CwT), and weekly carhoplatin-paclitaxel (wCwT), to standard 3-weekly treatment in women with newly diagnosed ovarian, fallopian tube, and primary peritoneal cancer

Authors: J Hook, SP Stenning, J Brenton, SB Kaye, IA McNeish, R Naik, T Perron, J Pe...
E-pub date: 1 Aug 2014
Journal name: JOURNAL OF CLINICAL ONCOLOGY

HER2 binds to the genome at specific regulatory sites of key genes in breast cancer

Authors: A Redmond, JS Carroll
E-pub date: 1 Aug 2014
Journal name: EUROPEAN JOURNAL OF CANCER

Quantitation of a spin polarization-induced nuclear Overhauser effect (SPINOE) between a hyperpolarized (13) C-labeled cell metabolite and water protons.

Authors: I Marco-Rius, SE Bohndiek, MI Kettunen, TJ Larkin, M Basharat, C Seeley, KM...
E-pub date: 1 Aug 2014
Journal name: Contrast Media Mol Imaging

Magnetic resonance imaging of tumour metabolism

Authors: KM Brindle, DE Hu, TB Rodrigues, EM Serrao, KN Timm
E-pub date: 1 Aug 2014
Journal name: EUROPEAN JOURNAL OF CANCER