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scFLAME: a unified generative model for interpretable clustering, hierarchical structure discovery and marker-gene identification in single-cell RNA-seq data

Authors: J Rao, M Jihad, G Biffi, PDW Kirk
Research group: Biffi Group
E-pub date: 11 Sep 2026
Journal name:

The transcription factor BACH1 couples chromatin priming and repression to enable macrophage plasticity and adaptation.

Authors: P Tzerpos, D Bojcsuk, K Bene, N Caballero-Sánchez, Z Parteka-Tojek, K Bane...
Research group: Carroll Group
E-pub date: 8 Sep 2026
Journal name: Immunity

Multi-stromal organoid co-culture modelling reveals epithelial-fibroblast heterogeneity in pancreatic cancer and pancreatitis.

Authors: W Li, M Jihad, EG Lloyd, M Zaccaria, G Mucciolo, G Nsubuga, A Koonan-Lonapp...
Research group: Biffi Group
E-pub date: 2 Sep 2026
Journal name: Nat Cell Biol

Imaging the hallmarks of cancer.

Authors: J Grimm, F Kiessling, KM Brindle, D Hanahan, SK Jain, P Lambin, T Lammers, ...
Research group:
E-pub date: 1 Sep 2026
Journal name: Nat Rev Cancer

Longitudinal transcriptomic profiling identifies predictors of response to neoadjuvant chemoimmunotherapy in triple-negative breast cancer: results from the NeoTRIPaPDL1 trial.

Authors: M Dugo, C-S Huang, D Egle, B Bermejo, RS Seitz, TJ Nielsen, C Zamagni, M Th...
Research group: Ali Group
E-pub date: 1 Sep 2026
Journal name: Ann Oncol

A tumour-derived organoid biobank maps cancer gene dependencies.

Authors: C Herranz-Ors, SG Bhosle, AE Beck, JGR Gilbert, G Picco, J Espejo Valle-Inc...
Research group: Brenton Group
E-pub date: 1 Sep 2026
Journal name: Nature

Correction: 6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells.

Authors: S Ros, J Flöter, I Kaymak, C Da Costa, A Houddane, S Dubuis, B Griffiths, ...
Research group:
E-pub date: 31 Aug 2026
Journal name: Oncogene

Paired mutation calling and spatial transcriptomics identify cellular neighborhoods associated with the neoplastic outcome of mouse colitis.

Authors: EB Moutin, LLH Chang, G Giavara, S Mehmed, M Colombé, C Boquetale, K Marks...
Research group:
E-pub date: 31 Aug 2026
Journal name: Nat Genet