Metabolic imaging distinguishes ovarian cancer subtypes and detects their early and variable responses to treatment.
Publication date: 6 Dec 2024
Authors: ML Chia, F Bulat, A Gaunt, S Ros, AJ Wright, A Sawle, L Porcu, M Vias, JD Brenton, KM Brindle
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Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer
Publication date: 3 Dec 2024
Authors: L Veghini, D Pasini, R Fang, P Delfino, D Filippini, C Neander, C Vicentini, E Fiorini, F Lupo, SL D’Agosto, C Carbone, A Agostini, G Piro, D Rosa, M Bevere, P Markus, D Behrens, C Luchini, RT Lawlor, A Scarpa, G Biffi, PF Cheung, JT Siveke, V Corbo
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In Vivo Assessment of Deep Vascular Patterns in Murine Colitis Using Optoacoustic Mesoscopic Imaging.
Publication date: 1 Dec 2024
Authors: A Buehler, EL Brown, E Nedoschill, M Eckstein, P Ludwig, F Wachter, H Mandelbaum, R Raming, M-E Oraiopoulou, L-P Paulus, U Rother, O Friedrich, MF Neurath, J Woelfle, MJ Waldner, F Knieling, SE Bohndiek, AP Regensburger
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Growth kinetics of high-grade serous ovarian cancer using longitudinal clinical data – implications for early detection
Publication date: 29 Nov 2024
Authors: B Narayanan, T Buddenkotte, H Smith, M Shah, S Freeman, D Hulse, G Funingana, M-L Alcaraz, M-C Ortuzar, J Brenton, P Pharoah, N Pashayan
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Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models.
Publication date: 26 Nov 2024
Authors: JS Bedia, Y-W Huang, AD Gonzalez, VD Gonzalez, I-G Funingana, Z Rahil, A Mike, A Lowar, M Vias, A Ashworth, JD Brenton, WJ Fantl
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Genome-aware annotation of CRISPR guides validates targets in variant cell lines and enhances discovery in screens.
Publication date: 26 Nov 2024
Authors: S Lam, JC Thomas, SP Jackson
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PTEN loss shapes macrophage dynamics in high grade serous ovarian carcinoma.
Publication date: 15 Nov 2024
Authors: S Spear, O Le Saux, HB Mirza, N Iyer, K Tyson, F Grundland Freile, JB Walton, C Woodman, S Jarvis, DP Ennis, C Aguirre Hernandez, Y Xu, P Spiliopoulou, JD Brenton, AP Costa-Pereira, DP Cook, BC Vanderhyden, HC Keun, E Triantafyllou, JN Arnold, IA McNeish
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Optimisation of Animal Handing and Timing of 2-deoxy-2-[18F]fluoro-D-glucose PET Tumour Imaging in Mice.
Publication date: 11 Nov 2024
Authors: RL Hesketh, DY Lewis, KM Brindle
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