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New paradigms for BRCA1/BRCA2 testing in women with ovarian cancer: results of the Genetic Testing in Epithelial Ovarian Cancer (GTEOC) study.
Authors: I Plaskocinska, H Shipman, J Drummond, E Thompson, V Buchanan, B Newcombe, ...
Research group: Brenton Group
E-pub date: 1 Oct 2016
Journal name: J Med Genet

Optimized p53 immunohistochemistry is an accurate predictor of TP53 mutation in ovarian carcinoma.
Authors: M Köbel, AM Piskorz, S Lee, S Lui, C LePage, F Marass, N Rosenfeld, A-M Me...
Research group: Brenton Group,
E-pub date: 1 Oct 2016
Journal name: J Pathol Clin Res

386P PISARRO: A EUTROC phase 1b study of APR-246 with carboplatin (C) and pegylated liposomal doxorubicin (PLD) in relapsed platinum-sensitive high grade serous ovarian cancer (HGSOC)
Authors: B Basu, C Gourley, H Gabra, IB Vergote, JD Brenton, L Abrahmsen, A Smith, M...
Research group: Brenton Group
E-pub date: 1 Oct 2016
Journal name: Annals of Oncology

G-quadruplex structures mark human regulatory chromatin.
Authors: R Hänsel-Hertsch, D Beraldi, SV Lensing, G Marsico, K Zyner, A Parry, M Di...
Research group: Narita Group, Balasubramanian Group
E-pub date: 1 Oct 2016
Journal name: Nat Genet

Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance.
Authors: M Secrier, X Li, N de Silva, MD Eldridge, G Contino, J Bornschein, S MacRae...
Research group: Bioinformatics
E-pub date: 1 Oct 2016
Journal name: Nat Genet

DSBCapture: in situ capture and sequencing of DNA breaks.
Authors: SV Lensing, G Marsico, R Hänsel-Hertsch, EY Lam, D Tannahill, S Balasubram...
Research group: Balasubramanian Group
E-pub date: 1 Oct 2016
Journal name: Nat Methods

rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome.
Authors: CK Kwok, G Marsico, AB Sahakyan, VS Chambers, S Balasubramanian
Research group: Balasubramanian Group
E-pub date: 1 Oct 2016
Journal name: Nat Methods

Global genome nucleotide excision repair is organized into domains that promote efficient DNA repair in chromatin.
Authors: S Yu, K Evans, P van Eijk, M Bennett, RM Webster, M Leadbitter, Y Teng, R W...
Research group: Jackson Group
E-pub date: 1 Oct 2016
Journal name: Genome Res