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Shared heritability and functional enrichment across six solid cancers.

Authors: X Jiang, HK Finucane, FR Schumacher, SL Schmit, JP Tyrer, Y Han, K Michaili...
E-pub date: 25 Jan 2019
Journal name: Nat Commun

A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.

Authors: SJ Walsh, S Omarjee, WRJD Galloway, TT-L Kwan, HF Sore, JS Parker, M Hyvön...
E-pub date: 21 Jan 2019
Journal name: Chem Sci

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

Authors: L Fachal, H Aschard, J Beesley, D Barnes, J Allen, S Kar, K Pooley, J Denni...
E-pub date: 18 Jan 2019
Journal name:

Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia.

Authors: F Paonessa, LD Evans, R Solanki, D Larrieu, S Wray, J Hardy, SP Jackson, FJ...
E-pub date: 15 Jan 2019
Journal name: Cell Rep

Correction: A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.

Authors: SJ Walsh, S Omarjee, WRJD Galloway, TT-L Kwan, HF Sore, JS Parker, M Hyvön...
E-pub date: 14 Jan 2019
Journal name: Chem Sci

Correction to: RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs.

Authors: P Murat, G Marsico, B Herdy, AT Ghanbarian, G Portella, S Balasubramanian
E-pub date: 11 Jan 2019
Journal name: Genome Biol

Genetic predisposition to mosaic Y chromosome loss in blood is associated with genomic instability in other tissues and susceptibility to non-haematological cancers

Authors: DJ Thompson, G Genovese, J Halvardson, JC Ulirsch, DJ Wright, C Terao, OB D...
E-pub date: 10 Jan 2019
Journal name:

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks.

Authors: G Balmus, D Pilger, J Coates, M Demir, M Sczaniecka-Clift, AC Barros, M Woo...
E-pub date: 8 Jan 2019
Journal name: Nat Commun