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Preclinical Modeling of Image-Guided Craniospinal Irradiation for Very-High-Risk Medulloblastoma.

Authors: SMC Smith, BM Bianski, BA Orr, G Harknett, A Onar-Thomas, RJ Gilbertson, TE...
E-pub date: 1 Mar 2019
Journal name: Int J Radiat Oncol Biol Phys

Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter.

Authors: A Sengar, JJ Vandana, VS Chambers, M Di Antonio, FR Winnerdy, S Balasubrama...
E-pub date: 20 Feb 2019
Journal name: Nucleic Acids Res

PIONEER- Pre-operative wIndOw study of letrozole plus PR agonist megestrol acetate versus letrozole aloNE in post-menopausal patients with ER-positive breast cancer

Authors: SS Kumar, J Benson, S McIntosh, P King, G Dougall, A Kateb, A-L Vallier, L ...
E-pub date: 15 Feb 2019
Journal name:

ESR1 mutations drive breast cancer metastasis by context-dependent alterations in adhesive and migratory properties

Authors: Z Li, A Bahreini, KM Levine, P Wang, N Tasdemir, MA Montanez, P Sundd, CT W...
E-pub date: 15 Feb 2019
Journal name: Cancer Research

Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models.

Authors: J Mieszczanek, LM van Tienen, AEK Ibrahim, DJ Winton, M Bienz
E-pub date: 13 Feb 2019
Journal name: Nat Commun

R-Loops as Cellular Regulators and Genomic Threats.

Authors: MP Crossley, M Bocek, KA Cimprich
E-pub date: 7 Feb 2019
Journal name: Mol Cell

IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma.

Authors: G Biffi, TE Oni, B Spielman, Y Hao, E Elyada, Y Park, J Preall, DA Tuveson
E-pub date: 1 Feb 2019
Journal name: Cancer Discov

BRCA Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma.

Authors: KK Lin, MI Harrell, AM Oza, A Oaknin, I Ray-Coquard, AV Tinker, E Helman, M...
E-pub date: 1 Feb 2019
Journal name: Cancer Discov