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Population exposure-safety and exposure-efficacy analyses for rucaparib in patients (pts) with recurrent ovarian carcinoma (rOC) from Study 10 and ARIEL2
Authors: GE Konecny, AM Oza, AV Tinker, A Oaknin, R Shapira-Frommer, I Ray-Coquard, ...
Research group: Brenton Group
E-pub date: 1 Oct 2020
Journal name: Gynecologic Oncology

Targeting LSD1 and FOXA1 in prostate cancer.
Authors: S Omarjee, JS Carroll
Research group: Carroll Group
E-pub date: 1 Oct 2020
Journal name: Nat Genet

The proapoptotic gene interferon regulatory factor-1 mediates the antiproliferative outcome of paired box 2 gene and tamoxifen.
Authors: S Wang, VS Somisetty, B Bai, I Chernukhin, H Niskanen, MU Kaikkonen, M Bell...
Research group: Carroll Group
E-pub date: 1 Oct 2020
Journal name: Oncogene

Increasing the sensitivity of hyperpolarized [15 N2 ]urea detection by serial transfer of polarization to spin-coupled protons.
Authors: F Kreis, AJ Wright, V Somai, R Katz-Brull, KM Brindle
Research group:
E-pub date: 1 Oct 2020
Journal name: Magn Reson Med

A multi spin echo pulse sequence with optimized excitation pulses and a 3D cone readout for hyperpolarized 13 C imaging.
Authors: V Somai, AJ Wright, M Fala, F Hesse, KM Brindle
Research group:
E-pub date: 1 Oct 2020
Journal name: Magn Reson Med

The phosphoinositide 3-kinase inhibitor alpelisib restores actin organization and improves proximal tubule dysfunction in vitro and in a mouse model of Lowe syndrome and Dent disease.
Authors: M Berquez, JR Gadsby, BP Festa, R Butler, SP Jackson, V Berno, A Luciani, O...
Research group: Jackson Group
E-pub date: 1 Oct 2020
Journal name: Kidney Int

A Comparative Photophysical Study of Structural Modifications of Thioflavin T-Inspired Fluorophores.
Authors: L-M Needham, J Weber, CM Pearson, DT Do, F Gorka, G Lyu, SE Bohndiek, TN Sn...
Research group: Bohndiek Group
E-pub date: 1 Oct 2020
Journal name: J Phys Chem Lett

The S enantiomer of 2-hydroxyglutarate increases central memory CD8 populations and improves CAR-T therapy outcome.
Authors: IP Foskolou, L Barbieri, A Vernet, D Bargiela, PP Cunha, P Velica, E Suh, S...
Research group: Pre-clinical imaging
E-pub date: 22 Sep 2020
Journal name: Blood Adv