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Triage-driven diagnosis of Barrett’s esophagus for early detection of esophageal adenocarcinoma using deep learning.
Authors: M Gehrung, M Crispin-Ortuzar, AG Berman, M O'Donovan, RC Fitzgerald, F Mark...
E-pub date: 1 May 2021
Journal name: Nat Med

Promises and challenges of adoptive T-cell therapies for solid tumours.
Authors: M Morotti, A Albukhari, A Alsaadi, M Artibani, JD Brenton, SM Curbishley, T...
E-pub date: 1 May 2021
Journal name: Br J Cancer

Population-based targeted sequencing of 54 candidate genes identifies PALB2 as a susceptibility gene for high-grade serous ovarian cancer.
Authors: H Song, EM Dicks, J Tyrer, M Intermaggio, G Chenevix-Trench, DD Bowtell, N ...
E-pub date: 1 May 2021
Journal name: J Med Genet

ILC2-driven innate immune checkpoint mechanism antagonizes NK cell anti-metastatic function in the lung.
Authors: TYF Halim, M Schuijs, S Png, A Richard, A Tsyben, G Hamm, J Stockis, C Garc...
E-pub date: 1 May 2021
Journal name: The Journal of Immunology

Interfaces between cellular responses to DNA damage and cancer immunotherapy.
Authors: D Pilger, LW Seymour, SP Jackson
E-pub date: 1 May 2021
Journal name: Genes Dev

G-quadruplexes are transcription factor binding hubs in human chromatin.
Authors: J Spiegel, SM Cuesta, S Adhikari, R Hänsel-Hertsch, D Tannahill, S Balasub...
E-pub date: 23 Apr 2021
Journal name: Genome Biol

Mutagenic mechanisms of cancer-associated DNA polymerase ϵ alleles.
Authors: M Herzog, E Alonso-Perez, I Salguero, J Warringer, DJ Adams, SP Jackson, F ...
E-pub date: 19 Apr 2021
Journal name: Nucleic Acids Res

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes.
Authors: SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, AG Deshwar, ...
E-pub date: 15 Apr 2021
Journal name: Cell