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Metabolic imaging with hyperpolarized [1-13C] pyruvate in patient-derived preclinical mouse models of breast cancer.

Authors: S Ros, AJ Wright, A Bruna, C Caldas, KM Brindle
E-pub date: 17 Sep 2021
Journal name: STAR Protoc

DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation.

Authors: RN Batra, A Lifshitz, AT Vidakovic, S-F Chin, A Sati-Batra, S-J Sammut, E P...
E-pub date: 13 Sep 2021
Journal name: Nat Commun

Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress.

Authors: RL Lloyd, V Urban, F Muñoz-Martínez, I Ayestaran, JC Thomas, C de Renty, ...
E-pub date: 7 Sep 2021
Journal name: Nucleic Acids Res

ZFTA Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors.

Authors: R Kupp, L Ruff, S Terranova, E Nathan, S Ballereau, R Stark, C Sekhar Reddy...
E-pub date: 1 Sep 2021
Journal name: Cancer Discov

Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion-Positive Supratentorial Ependymomas.

Authors: T Zheng, DR Ghasemi, K Okonechnikov, A Korshunov, M Sill, KK Maass, P Benit...
E-pub date: 1 Sep 2021
Journal name: Cancer Discov

Mechanically matching the rheological properties of brain tissue for drug-delivery in human glioblastoma models.

Authors: CC Parkins, JH McAbee, L Ruff, A Wendler, R Mair, RJ Gilbertson, C Watts, O...
E-pub date: 1 Sep 2021
Journal name: Biomaterials

ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.

Authors: A Arabzade, Y Zhao, S Varadharajan, H-C Chen, S Jessa, B Rivas, AJ Stuckert...
E-pub date: 1 Sep 2021
Journal name: Cancer Discov

Multiparametric MRI of early tumor response to immune checkpoint blockade in metastatic melanoma.

Authors: D Lau, MA McLean, AN Priest, AB Gill, F Scott, I Patterson, B Carmo, F Riem...
E-pub date: 1 Sep 2021
Journal name: J Immunother Cancer