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The dCMP deaminase DCTD and the E3 ligase TOPORS are central mediators of decitabine cytotoxicity

Authors: CJ Carnie, MJ Götz, CS Palma-Chaundler, P Weickert, AR Wanders, A Serrano-...
Research group: Jackson Group
E-pub date: 23 Dec 2023
Journal name:

RAD54L2 counters TOP2-DNA adducts to promote genome stability.

Authors: G D'Alessandro, DA Morales-Juarez, SL Richards, KC Nitiss, A Serrano-Benite...
Research group: Jackson Group
E-pub date: 8 Dec 2023
Journal name: Sci Adv

Deep learning-based segmentation of multisite disease in ovarian cancer.

Authors: T Buddenkotte, L Rundo, R Woitek, L Escudero Sanchez, L Beer, M Crispin-Ort...
Research group: Brenton Group
E-pub date: 7 Dec 2023
Journal name: Eur Radiol Exp

Omentum-derived matrix enables the study of metastatic ovarian cancer and stromal cell functions in a physiologically relevant environment.

Authors: LJ Neilson, D Cartwright, M Risteli, EM Jokinen, L McGarry, T Sandvik, K Ni...
Research group: Brenton Group
E-pub date: 1 Dec 2023
Journal name: Matrix Biol Plus

Pan-cancer analysis of antibody-drug conjugate targets and putative predictors of treatment response.

Authors: C Bosi, Á Bartha, B Galbardi, G Notini, MM Naldini, L Licata, G Viale, M M...
Research group: Ali Group
E-pub date: 1 Dec 2023
Journal name: Eur J Cancer

KCNQ potassium channels modulate Wnt activity in gastro-oesophageal adenocarcinomas.

Authors: D Shorthouse, L Zhuang, EP Rahrmann, C Kosmidou, K Wickham Rahrmann, M Hall...
Research group: Gilbertson Group
E-pub date: 1 Dec 2023
Journal name: Life Sci Alliance

Abstract B079: Molecular determinants of sensitivity to Polatuzumab-Vedotin

Authors: SR Corcoran, J Choi, RE Fenner, X Yu, S Scheich, G Schevchenko, EK Papachri...
Research group: Proteomics
E-pub date: 1 Dec 2023
Journal name: Molecular Cancer Therapeutics

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus

Authors: J van Lopik, A Alizada, M-A Trapotsi, GJ Hannon, S Bornelöv, B Czech Nicho...
Research group: Hannon Group
E-pub date: 13 Nov 2023
Journal name: Nat Commun