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Decay of driver mutations shapes the landscape of intestinal transformation.

Authors: FC Lourenço, ID Sadien, K Wong, S Adler, A Sawle, LS Santana, L Hazelwood,...
E-pub date: 1 Jan 2026
Journal name: Nature

Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models.

Authors: M Schoof, T Zheng, M Sill, R Imle, A Cais, L Altendorf, A Fürst, N Hofmann...
E-pub date: 1 Jan 2026
Journal name: Nat Genet

A toolkit for generating virtual brightfield images of histological and immunohistochemical stains from multiplexed data with AI-based channel selection and image enhancement

Authors: T Whitmarsh, M Al Sa’d, EG Solares, A Molaeinezhad, MO Irfan, C Mulvey, M...
E-pub date: 1 Jan 2026
Journal name: Front Bioinform

Evaluating progesterone receptor agonist megestrol plus letrozole for women with early-stage estrogen-receptor-positive breast cancer: the window-of-opportunity, randomized, phase 2b, PIONEER trial.

Authors: RA Burrell, S Kumar, E Provenzano, C Pike, A Dayimu, SA McIntosh, V Pitsini...
E-pub date: 1 Jan 2026
Journal name: Nat Cancer

Cryo-EM structures of NHEJ assemblies with nucleosomes.

Authors: C Hall, P Frit, A Kefala-Stavridi, A Pelletier, SW Hardwick, H Amin, MK Bil...
E-pub date: 24 Dec 2025
Journal name: Nat Commun

Somatic evolution following cancer treatment in normal tissue.

Authors: O Pich, S Ward, A Rowan, C Naceur-Lombardelli, O Shutkever, C Martinez-Ruiz...
E-pub date: 10 Dec 2025
Journal name: Nature

Transcription factor switching drives subtype-specific pancreatic cancer.

Authors: SV Rao, L Young, D Cheeseman, S Flynn, N Krebs, D-L Couturier, S Mack, R Br...
E-pub date: 1 Dec 2025
Journal name: Nat Genet

Loss of IDH1 and IDH2 mutations during the evolution of metastatic chondrosarcoma.

Authors: W Cross, I Lyskjær, C Davies, A Bunkum, AM Rocha, T Lesluyes, F Amary, R T...
E-pub date: 26 Nov 2025
Journal name: Genome Biol