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Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing.

Authors: R Roy, B Meier, AD McAinsh, HM Feldmann, SP Jackson
Research group: Jackson Group
E-pub date: 2 Jan 2004
Journal name: Journal of Biological Chemistry

Detection of apoptosis using the C2A domain of synaptotagmin I.

Authors: H-I Jung, MI Kettunen, B Davletov, KM Brindle
Research group: Brindle Group
E-pub date: 1 Jan 2004
Journal name: Bioconjugate Chemistry

Tumor cell-derived nitric oxide is involved in the immune-rejection of an immunogenic murine lymphoma.

Authors: D-E Hu, SOM Dyke, AM Moore, LL Thomsen, KM Brindle
Research group: Brindle Group
E-pub date: 1 Jan 2004
Journal name: Cancer Research

p53 prevents the accumulation of double-strand DNA breaks at stalled-replication forks induced by UV in human cells.

Authors: S Squires, JA Coates, M Goldberg, LH Toji, SP Jackson, DJ Clarke, RT Johnso...
Research group: Jackson Group
E-pub date: 1 Jan 2004
Journal name: Cell Cycle

Activation of the DNA damage response by telomere attrition: A passage to cellular senescence

Authors: PM Reaper, F D'Adda Di Fagagna, SP Jackson
Research group: Jackson Group
E-pub date: 1 Jan 2004
Journal name: Cell Cycle

Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer.

Authors: L Ying, JJ Green, H Li, D Klenerman, S Balasubramanian
Research group: Balasubramanian Group
E-pub date: 9 Dec 2003
Journal name: Proc Natl Acad Sci U S A

Free energy lights the path toward more effective RNAi.

Authors: JM Silva, R Sachidanandam, GJ Hannon
Research group: Hannon Group
E-pub date: 1 Dec 2003
Journal name: Nat Genet

The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes.

Authors: J-J Song, J Liu, NH Tolia, J Schneiderman, SK Smith, RA Martienssen, GJ Han...
Research group: Hannon Group
E-pub date: 1 Dec 2003
Journal name: Nat Struct Biol