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Modelling the micro- and macro- environment of pancreatic cancer: from patients to pre-clinical models and back.
Authors: EG Lloyd, JA HenrĂ­quez, G Biffi
E-pub date: 1 Apr 2024
Journal name: Dis Model Mech

Abstract 2945: Using pooled minimal genome-wide sgRNA libraries to drive oncology drug discovery
Authors: S Lukasiak, A Kalinka, N Gupta, K Saeed, A Papadopoulos, U McDermott, GJ Ha...
E-pub date: 22 Mar 2024
Journal name: Cancer Research

Abstract 4355: Characterizing HRD in ovarian cancer: Insights from copy number signatures
Authors: A Hawari, A Tapinos, CJ Kramer, AJ Gruber, R Houlston, J Brenton, D Wedge
E-pub date: 22 Mar 2024
Journal name: Cancer Research

An Upstream G-Quadruplex DNA Structure Can Stimulate Gene Transcription.
Authors: Y Chen, A Simeone, L Melidis, SM Cuesta, D Tannahill, S Balasubramanian
Research group: Balasubramanian Group
E-pub date: 15 Mar 2024
Journal name: ACS Chem Biol

Proteogenomic analysis of enriched HGSOC tumor epithelium identifies prognostic signatures and therapeutic vulnerabilities.
Authors: NW Bateman, T Abulez, AR Soltis, A McPherson, S Choi, DW Garsed, A Pandey, ...
E-pub date: 13 Mar 2024
Journal name: NPJ Precis Oncol

A Dirichlet-multinomial mixed model for determining differential abundance of mutational signatures
Authors: L Morrill GavarrĂł, D-L Couturier, F Markowetz
E-pub date: 10 Mar 2024
Journal name:

scAbsolute: measuring single-cell ploidy and replication status.
Authors: MP Schneider, AE Cullen, J Pangonyte, J Skelton, H Major, E Van Oudenhove, ...
E-pub date: 4 Mar 2024
Journal name: Genome Biol

Large-scale genome-wide association study of 398,238 women unveils seven novel loci associated with high-grade serous epithelial ovarian cancer risk.
Authors: DR Barnes, JP Tyrer, J Dennis, G Leslie, MK Bolla, M Lush, AM Aeilts, K Ait...
E-pub date: 4 Mar 2024
Journal name: