Publications

Structural Identification of Major Molecular Determinants for Phosphotyrosine Recognition in Tyrosine Kinases Reveals Tumour Promoting and Suppressive Functions.

Authors: N Cheng, LR Millán-Barea, M Creixell, AR Barr, YW Kong, BA Joughin, CK Lop...

Research group: Creixell Group

E-pub date: 11 Jun 2025

Journal name: bioRxiv

Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.

Authors: M Delgado-Ortet, V Bura, I-G Funingana, D Hulse, L Rundo, JD Brenton, E Sal...

Research group: Brenton Group

E-pub date: 5 Jun 2025

Journal name: Frontiers in Oncology

DNA G-quadruplex structures act as functional elements in α- and β-globin enhancers.

Authors: C Doyle, K Herka, SM Flynn, L Melidis, S Dhir, S Schoenfelder, D Tannahill,...

Research group: Balasubramanian Group

E-pub date: 4 Jun 2025

Journal name: Genome Biology

Early Radiation Therapy Response Assessment using Multi-scale Photoacoustic Imaging

Authors: TL Lefebvre, M-E Oraiopoulou, EV Bunce, TR Else, LC Wright, MA Golinska, L ...

Research group: Bohndiek Group

E-pub date: 3 Jun 2025

Journal name:

1P Whole-genome sequencing (WGS) measures of theta-mediated end joining (TMEJ) predict PARP inhibitors (PARPi) benefit

Authors: IG Funingana, J Ambrose, P Smith, T Bradley, L Porcu, AA Sosinsky, JD Brent...

Research group: Brenton Group

E-pub date: 1 Jun 2025

Journal name: ESMO Open

KDM4C inhibition blocks tumor growth in basal breast cancer by promoting cathepsin L-mediated histone H3 cleavage.

Authors: Z Li, G Peluffo, LE Stevens, X Qiu, M Seehawer, A Tawawalla, X-Y Huang, SB ...

Research group: Carroll Group

E-pub date: 1 Jun 2025

Journal name: Nat Genet

CHD8 interacts with BCL11A to induce oncogenic transcription in triple negative breast cancer.

Authors: M Waterhouse, K Lazarus, MF Santolla, S Pensa, E Williams, AJQ Siu, H Moham...

Research group: Carroll Group

E-pub date: 1 Jun 2025

Journal name: EMBO J

Optical control of gene expression using a DNA G-quadruplex targeting reversible photoswitch.

Authors: X Zhang, S Dhir, L Melidis, Y Chen, Z Yu, A Simeone, J Spiegel, S Adhikari,...

Research group: Balasubramanian Group

E-pub date: 1 Jun 2025

Journal name: Nat Chem

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Structural Identification of Major Molecular Determinants for Phosphotyrosine Recognition in Tyrosine Kinases Reveals Tumour Promoting and Suppressive Functions.

Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.

DNA G-quadruplex structures act as functional elements in α- and β-globin enhancers.

Early Radiation Therapy Response Assessment using Multi-scale Photoacoustic Imaging

1P Whole-genome sequencing (WGS) measures of theta-mediated end joining (TMEJ) predict PARP inhibitors (PARPi) benefit

KDM4C inhibition blocks tumor growth in basal breast cancer by promoting cathepsin L-mediated histone H3 cleavage.

CHD8 interacts with BCL11A to induce oncogenic transcription in triple negative breast cancer.

Optical control of gene expression using a DNA G-quadruplex targeting reversible photoswitch.

Themes

Filters

Research Groups

Core Facilities

Start date

End date

Structural Identification of Major Molecular Determinants for Phosphotyrosine Recognition in Tyrosine Kinases Reveals Tumour Promoting and Suppressive Functions.

Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.

DNA G-quadruplex structures act as functional elements in α- and β-globin enhancers.

Early Radiation Therapy Response Assessment using Multi-scale Photoacoustic Imaging

1P Whole-genome sequencing (WGS) measures of theta-mediated end joining (TMEJ) predict PARP inhibitors (PARPi) benefit

KDM4C inhibition blocks tumor growth in basal breast cancer by promoting cathepsin L-mediated histone H3 cleavage.

CHD8 interacts with BCL11A to induce oncogenic transcription in triple negative breast cancer.

Optical control of gene expression using a DNA G-quadruplex targeting reversible photoswitch.