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Prolonged response of relapsed high grade serous ovarian carcinoma to the oral angiokinase inhibitor nintedanib in a patient with a germline BRCA1 mutation.
Authors: HH Wong, C Parkinson, JA Ledermann, JD Brenton, M Merger, A Shaw, A Patters...
Research group: Brenton Group
E-pub date: 1 Aug 2012
Journal name: Gynecol Oncol Case Rep

FoxA1 is a key mediator of hormonal response in breast and prostate cancer.
Authors: JLL Robinson, JS Carroll
Research group: Carroll Group
E-pub date: 1 Aug 2012
Journal name: Front Endocrinol (Lausanne)

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.
Authors: M Kalyuga, D Gallego-Ortega, HJ Lee, DL Roden, MJ Cowley, CE Caldon, A Ston...
Research group: Carroll Group
E-pub date: 1 Aug 2012
Journal name: PLoS Biol

Rags connect mTOR and autophagy.
Authors: M Narita, K Inoki
Research group: Narita Group
E-pub date: 1 Aug 2012
Journal name: Small GTPases

Improving image quality by accounting for changes in water temperature during a photoacoustic tomography scan.
Authors: D Van de Sompel, LS Sasportas, A Dragulescu-Andrasi, S Bohndiek, SS Gambhir
Research group: Bohndiek Group
E-pub date: 1 Aug 2012
Journal name: PLoS One

Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.
Authors: RE McIntyre, P Lakshminarasimhan Chavali, O Ismail, DM Carragher, G Sanchez...
Research group: Jackson Group
E-pub date: 1 Aug 2012
Journal name: PLoS Genet

BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair.
Authors: JR Chapman, AJ Sossick, SJ Boulton, SP Jackson
Research group: Jackson Group
E-pub date: 1 Aug 2012
Journal name: J Cell Sci

Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation.
Authors: T Chandra, K Kirschner, J-Y Thuret, BD Pope, T Ryba, S Newman, K Ahmed, SA ...
Research group: Narita Group
E-pub date: 27 Jul 2012
Journal name: Mol Cell