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Non-coding stem-bulge RNAs are required for cell proliferation and embryonic development in C. elegans.
Authors: MP Kowalski, HA Baylis, T Krude
Research group: Crossley Group
E-pub date: 1 Jun 2015
Journal name: J Cell Sci

Targeted Detection of G-Quadruplexes in Cellular RNAs.
Authors: CK Kwok, S Balasubramanian
Research group: Balasubramanian Group
E-pub date: 1 Jun 2015
Journal name: Angewandte Chemie - International Edition

Imaging metabolism with hyperpolarized (13)C-labeled cell substrates.
Authors: KM Brindle
Research group:
E-pub date: 27 May 2015
Journal name: J Am Chem Soc

EUTROC PiSARRO: A phase Ib study combining APR-246 with standard chemotherapy in platinum sensitive relapsed high grade serous ovarian carcinoma (HGSOC).
Authors: C Gourley, H Gabra, I Vergote, B Basu, J Brenton, M Von Euler, U Björklund...
Research group: Brenton Group
E-pub date: 20 May 2015
Journal name: Journal of Clinical Oncology

A randomized, placebo-controlled phase II trial comparing gemcitabine monotherapy to gemcitabine in combination with AZD 1775 (MK 1775) in women with recurrent, platinum-resistant epithelial ovarian, primary peritoneal, or Fallopian tube cancers: Trial of Princess Margaret, Mayo, Chicago, and California consortia.
Authors: S Lheureux, JI Weberpals, AE Wahner Hendrickson, GF Fleming, A Olawaiye, I ...
Research group: Brenton Group
E-pub date: 20 May 2015
Journal name: Journal of Clinical Oncology

Assessment of clinical applications of circulating tumor DNA using an enhanced TAm-Seq platform.
Authors: V Plagnol, A Lawson, T Forshew, A Fahem, J Brenton, D Gale, N Rosenfeld
Research group: Brenton Group,
E-pub date: 20 May 2015
Journal name: Journal of Clinical Oncology

Results of ARIEL2: A Phase 2 trial to prospectively identify ovarian cancer patients likely to respond to rucaparib using tumor genetic analysis.
Authors: IA McNeish, AM Oza, RL Coleman, CL Scott, GE Konecny, A Tinker, DM O'Malley...
Research group: Brenton Group
E-pub date: 20 May 2015
Journal name: Journal of Clinical Oncology

An epigenetic memory of pregnancy in the mouse mammary gland.
Authors: CO Dos Santos, E Dolzhenko, E Hodges, AD Smith, GJ Hannon
Research group: Hannon Group
E-pub date: 19 May 2015
Journal name: Cell Reports