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Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks.

Authors: AE Bilsland, A Pugliese, Y Liu, J Revie, S Burns, C McCormick, CJ Cairney, ...
E-pub date: 1 Sep 2015
Journal name: Neoplasia

A flow cytometry-based method to simplify the analysis and quantification of protein association to chromatin in mammalian cells.

Authors: JV Forment, SP Jackson
E-pub date: 1 Sep 2015
Journal name: Nat Protoc

A Bayesian adaptive design for biomarker trials with linked treatments.

Authors: JMS Wason, JE Abraham, RD Baird, I Gournaris, A-L Vallier, JD Brenton, HM E...
E-pub date: 1 Sep 2015
Journal name: Br J Cancer

Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition.

Authors: M Sadaie, C Dillon, M Narita, ARJ Young, CJ Cairney, LS Godwin, CJ Torrance...
E-pub date: 1 Sep 2015
Journal name: Mol Biol Cell

An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes.

Authors: KM Mohankumar, DS Currle, E White, N Boulos, J Dapper, C Eden, B Nimmervoll...
E-pub date: 31 Aug 2015
Journal name: Nat Genet

Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study.

Authors: LM Hoffman, M Fouladi, J Olson, VM Daryani, CF Stewart, C Wetmore, M Kocak,...
E-pub date: 31 Aug 2015
Journal name: Childs Nerv Syst

The return of metabolism: biochemistry and physiology of the pentose phosphate pathway.

Authors: A Stincone, A Prigione, T Cramer, MMC Wamelink, K Campbell, E Cheung, V Oli...
E-pub date: 31 Aug 2015
Journal name: Biol Rev Camb Philos Soc

Retinoblastoma protein promotes oxidative phosphorylation through upregulation of glycolytic genes in oncogene-induced senescent cells.

Authors: S-I Takebayashi, H Tanaka, S Hino, Y Nakatsu, T Igata, A Sakamoto, M Narita...
E-pub date: 31 Aug 2015
Journal name: Aging Cell