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Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer.

Authors: TW Owens, RL Rogers, S Best, A Ledger, A-M Mooney, A Ferguson, P Shore, A S...
E-pub date: 15 Sep 2014
Journal name: Cancer Res

A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response.

Authors: M Blasius, SA Wagner, C Choudhary, J Bartek, SP Jackson
E-pub date: 15 Sep 2014
Journal name: Genes Dev

Dephosphorylation of tyrosine 393 in argonaute 2 by protein tyrosine phosphatase 1B regulates gene silencing in oncogenic RAS-induced senescence.

Authors: M Yang, AD Haase, F-K Huang, G Coulis, KD Rivera, BC Dickinson, CJ Chang, D...
E-pub date: 4 Sep 2014
Journal name: Mol Cell

The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma.

Authors: X He, L Zhang, Y Chen, M Remke, D Shih, F Lu, H Wang, Y Deng, Y Yu, Y Xia, ...
E-pub date: 1 Sep 2014
Journal name: Nat Med

SANTA: quantifying the functional content of molecular networks.

Authors: AJ Cornish, F Markowetz
E-pub date: 1 Sep 2014
Journal name: PLoS Comput Biol

Arid1A Role in Cell Cycle Regulation and Proliferation in Mouse and Human Gynaecological Tissues Reveals Potential Therapeutic Targets

Authors: I Gounaris, J Brenton
E-pub date: 1 Sep 2014
Journal name: Annals of Oncology

Phosphorylation of activating transcription factor-2 (ATF-2) within the activation domain is a key determinant of sensitivity to tamoxifen in breast cancer.

Authors: B Rudraraju, M Droog, TMA Abdel-Fatah, W Zwart, A Giannoudis, MI Malki, D M...
E-pub date: 1 Sep 2014
Journal name: Breast Cancer Res Treat

883PDPRELIMINARY RESULTS OF ARIEL2, A PHASE 2 OPEN-LABEL STUDY TO IDENTIFY OVARIAN CANCER PATIENTS LIKELY TO RESPOND TO RUCAPARIB.

Authors: I McNeish, R Coleman, AM Oza, GE Konecny, D O'Malley, G Kichenadasse, C Sco...
E-pub date: 1 Sep 2014
Journal name: Ann Oncol