Publications

PISARRO: A EUTROC phase 1b study of APR-246 with carboplatin (C) and pegylated liposomal doxorubicin (PLD) in relapsed platinum-sensitive high grade serous ovarian cancer (HGSOC)

Authors: B Basu, C Gourley, H Gabra, IB Vergote, JD Brenton, L Abrahmsen, A Smith, M...

E-pub date: 1 Oct 2016

Journal name: Annals of Oncology

G-quadruplex structures mark human regulatory chromatin.

Authors: R Hänsel-Hertsch, D Beraldi, SV Lensing, G Marsico, K Zyner, A Parry, M Di...

E-pub date: 1 Oct 2016

Journal name: Nat Genet

Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance.

Authors: M Secrier, X Li, N de Silva, MD Eldridge, G Contino, J Bornschein, S MacRae...

E-pub date: 1 Oct 2016

Journal name: Nat Genet

DSBCapture: in situ capture and sequencing of DNA breaks.

Authors: SV Lensing, G Marsico, R Hänsel-Hertsch, EY Lam, D Tannahill, S Balasubram...

E-pub date: 1 Oct 2016

Journal name: Nat Methods

rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome.

Authors: CK Kwok, G Marsico, AB Sahakyan, VS Chambers, S Balasubramanian

E-pub date: 1 Oct 2016

Journal name: Nat Methods

Global genome nucleotide excision repair is organized into domains that promote efficient DNA repair in chromatin.

Authors: S Yu, K Evans, P van Eijk, M Bennett, RM Webster, M Leadbitter, Y Teng, R W...

E-pub date: 1 Oct 2016

Journal name: Genome Res

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

Authors: DG Hu, LA Selth, GA Tarulli, R Meech, D Wijayakumara, A Chanawong, R Russel...

E-pub date: 1 Oct 2016

Journal name: Cancer Res

G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 status.

Authors: P Agarwal, SP Jackson

E-pub date: 1 Oct 2016

Journal name: Cancer Lett

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PISARRO: A EUTROC phase 1b study of APR-246 with carboplatin (C) and pegylated liposomal doxorubicin (PLD) in relapsed platinum-sensitive high grade serous ovarian cancer (HGSOC)

G-quadruplex structures mark human regulatory chromatin.

Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance.

DSBCapture: in situ capture and sequencing of DNA breaks.

rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome.

Global genome nucleotide excision repair is organized into domains that promote efficient DNA repair in chromatin.

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 status.

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Filters

Research Groups

Core Facilities

Start date

End date

PISARRO: A EUTROC phase 1b study of APR-246 with carboplatin (C) and pegylated liposomal doxorubicin (PLD) in relapsed platinum-sensitive high grade serous ovarian cancer (HGSOC)

G-quadruplex structures mark human regulatory chromatin.

Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance.

DSBCapture: in situ capture and sequencing of DNA breaks.

rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome.

Global genome nucleotide excision repair is organized into domains that promote efficient DNA repair in chromatin.

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 status.