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Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study.
Authors: HR Ali, L Chlon, PDP Pharoah, F Markowetz, C Caldas
E-pub date: 1 Dec 2016
Journal name: PLoS Med

Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study.
Authors: CA Parkinson, D Gale, AM Piskorz, H Biggs, C Hodgkin, H Addley, S Freeman, ...
E-pub date: 1 Dec 2016
Journal name: PLoS Med

Feasibility of monitoring response to the PARP inhibitor rucaparib with targeted deep sequencing of circulating tumor DNA (ctDNA) in women with high grade ovarian carcinoma on the ARIEL2 trial
Authors: AM Piskorz, KK Lin, J Morris, E Mann, A Oza, RL Coleman, DM O'Malley, M Fri...
E-pub date: 1 Dec 2016
Journal name: European Journal of Cancer

The relationship between endogenous thymidine concentrations and [(18)F]FLT uptake in a range of preclinical tumour models.
Authors: K Heinzmann, DJ Honess, DY Lewis, D-M Smith, C Cawthorne, H Keen, S Heskamp...
E-pub date: 1 Dec 2016
Journal name: EJNMMI Res

Prelamin A impairs 53BP1 nuclear entry by mislocalizing NUP153 and disrupting the Ran gradient.
Authors: AM Cobb, D Larrieu, DT Warren, Y Liu, S Srivastava, AJO Smith, RP Bowater, ...
E-pub date: 1 Dec 2016
Journal name: Aging Cell

A phylogenetic latent feature model for clonal deconvolution
Authors: F Marass, F Mouliere, K Yuan, N Rosenfeld, F Markowetz
E-pub date: 1 Dec 2016
Journal name: Annals of Applied Statistics

The C/EBPδ protein is stabilized by estrogen receptor α activity, inhibits SNAI2 expression and associates with good prognosis in breast cancer.
Authors: D Mendoza-Villanueva, K Balamurugan, HR Ali, S-R Kim, S Sharan, RC Johnson,...
E-pub date: 1 Dec 2016
Journal name: Oncogene

Different DNA End Configurations Dictate Which NHEJ Components Are Most Important for Joining Efficiency.
Authors: HHY Chang, G Watanabe, CA Gerodimos, T Ochi, TL Blundell, SP Jackson, MR Li...
E-pub date: 18 Nov 2016
Journal name: J Biol Chem