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PISARRO: A EUTROC phase 1b study of APR-246 with carboplatin (C) and pegylated liposomal doxorubicin (PLD) in relapsed platinum-sensitive high grade serous ovarian cancer (HGSOC)
Authors: B Basu, C Gourley, H Gabra, IB Vergote, JD Brenton, L Abrahmsen, A Smith, M...
E-pub date: 1 Oct 2016
Journal name: Annals of Oncology

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.
Authors: DG Hu, LA Selth, GA Tarulli, R Meech, D Wijayakumara, A Chanawong, R Russel...
E-pub date: 1 Oct 2016
Journal name: Cancer Res

G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 status.
Authors: P Agarwal, SP Jackson
E-pub date: 1 Oct 2016
Journal name: Cancer Lett

Synthetic lethality between PAXX and XLF in mammalian development.
Authors: G Balmus, AC Barros, PWG Wijnhoven, C Lescale, HL Hasse, K Boroviak, C le S...
E-pub date: 1 Oct 2016
Journal name: Genes Dev

A saltationist theory of cancer evolution.
Authors: F Markowetz
E-pub date: 28 Sep 2016
Journal name: Nat Genet

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.
Authors: A Bruna, OM Rueda, W Greenwood, AS Batra, M Callari, RN Batra, K Pogrebniak...
E-pub date: 22 Sep 2016
Journal name: Cell

Following Metabolism in Living Microorganisms by Hyperpolarized (1)H NMR.
Authors: P Dzien, A Fages, G Jona, KM Brindle, M Schwaiger, L Frydman
E-pub date: 21 Sep 2016
Journal name: J Am Chem Soc

Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks.
Authors: P Chanut, S Britton, J Coates, SP Jackson, P Calsou
E-pub date: 19 Sep 2016
Journal name: Nat Commun