Tetramethylpyridiniumporphyrazines–a new class of G-quadruplex inducing and stabilising ligands.

Abstract:

3,4-Tetramethylpyridiniumporphyrazines bind strongly and selectively to human telomeric G-quadruplex DNA, inducing the formation of an antiparallel quadruplex in a process that mimics molecular chaperones.

Authors:

DPN Gonçalves, R Rodriguez, S Balasubramanian, JKM Sanders

Journal:

Chem Commun (Camb)

Citation info:

(45):4685-4687

Publication date:

7th Dec 2006

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