Special issue on “deuterium metabolic imaging”.

Abstract:: Deuterium metabolic imaging (DMI) has emerged as a powerful non-invasive approach for probing tissue metabolism in vivo via detection of 2H-labeled substrates and their downstream products. Spatially resolved mapping of substrate uptake and metabolic fate enables direct insight into central metabolic pathways, such as glycolysis, the TCA cycle and lipid metabolism. Over the years, DMI has seen increasing adoption as a valuable metabolic imaging technique, with growing relevance for both preclinical research and clinical translation.

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