Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c-MYC.
- Abstract:
- Single molecule fluorescence spectroscopy has been employed to resolve the conformational heterogeneity, hybridization kinetics and study mutational effects on the c-MYC promoter G-quadruplex.
- Authors:
- PS Shirude, L Ying, S Balasubramanian
- Journal:
- Chem Commun (Camb)
- Citation info:
- (17):2007-2009
- Publication date:
- 7th May 2008
- Full text
- DOI