Recent developments in the encoding and deconvolution of combinatorial libraries.

Abstract:

The value of molecular libraries generated by combinatorial methods is largely dependent on the ease and ability to deconvolute or decode the structure of compounds of interest after screening the library. Following the introduction of promising concepts in the early 1990s, there has been considerable progress in the development and refinement of methodologies to address this issue.

Authors:

C Barnes, S Balasubramanian

Journal:

Curr Opin Chem Biol

Citation info:

4(3):346-350

Publication date:

1st Jun 2000

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