Putting the DOT on IL1A.
- Abstract:
- IL-1α is an upstream component of the senescence-associated secretory phenotype. In this issue, Leon et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202008101) show that DOT1L-mediated H3K79 methylation at the IL1A gene plays a key role in its induction during oncogene-induced senescence.
- Authors:
- I Olan, M Narita
- Journal:
- J Cell Biol
- Citation info:
- 220(8)
- Publication date:
- 2nd Aug 2021
- Full text
- DOI