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ThX – a next-generation probe for the early detection of amyloid aggregates.
Authors: L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe...
E-pub date: 21 Feb 2020
Journal name: Chem Sci

PIK3R1W624R Is an Actionable Mutation in High Grade Serous Ovarian Carcinoma.
Authors: C D'Ambrosio, J Erriquez, M Arigoni, S Capellero, G Mittica, E Ghisoni, F B...
E-pub date: 14 Feb 2020
Journal name: Cells

PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1.
Authors: R Belotserkovskaya, E Raga Gil, N Lawrence, R Butler, G Clifford, MD Wilson...
E-pub date: 10 Feb 2020
Journal name: Nat Commun

Chronic irradiation of human cells reduces histone levels and deregulates gene expression.
Authors: DJ Lowe, M Herzog, T Mosler, H Cohen, S Felton, P Beli, K Raj, Y Galanty, S...
E-pub date: 10 Feb 2020
Journal name: Sci Rep

Inferring structural variant cancer cell fraction.
Authors: M Cmero, K Yuan, CS Ong, J Schröder, PCAWG Evolution and Heterogeneity Wo...
E-pub date: 5 Feb 2020
Journal name: Nat Commun

Total synthesis and biological evaluation of simplified aplyronine analogues as synthetically tractable anticancer agents.
Authors: TR Pettigrew, RJ Porter, SJ Walsh, MP Housden, NYS Lam, JS Carroll, JS Park...
E-pub date: 4 Feb 2020
Journal name: Chem Commun (Camb)

A Spontaneous Ring-Opening Reaction Leads to a Repair-Resistant Thymine Oxidation Product in Genomic DNA.
Authors: AB Sahakyan, A Mahtey, F Kawasaki, S Balasubramanian
E-pub date: 3 Feb 2020
Journal name: Chembiochem

The evolutionary history of 2,658 cancers.
Authors: M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, TJ M...
E-pub date: 1 Feb 2020
Journal name: Nature