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An organoid CRISPRi screen revealed that SOX9 primes human fetal lung tip progenitors to receive WNT and RTK signals
Authors: D Sun, OL Batlle, J van den Ameele, J Thomas, P He, K Lim, W Tang, C Xu, K ...
E-pub date: 28 Jan 2022
Journal name:

Hyperpolarised 13C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer.
Authors: N Sushentsev, MA McLean, AY Warren, AJV Benjamin, C Brodie, A Frary, AB Gil...
E-pub date: 24 Jan 2022
Journal name: Nat Commun

CELL-AUTONOMOUS HEDGEHOG SIGNALING CONTROLS TH17 DIFFERENTIATION TO DRIVE INTESTINAL INFLAMMATION AND IS A DRUGGABLE TARGET FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE
Authors: J Hanna, F Beke, L O'Brien, C Kapeni, H-C Chen, V Carbonaro, A Kim, TE Adol...
E-pub date: 22 Jan 2022
Journal name: Inflammatory Bowel Diseases

DOP48 Hedgehog signalling controls Th17 differentiation to drive intestinal inflammation and is a druggable target for the treatment of IBD
Authors: J Hanna, F Beke, L O’Brien, C Kapeni, HC Chen, V Carbonaro, A Kim, K Kish...
E-pub date: 21 Jan 2022
Journal name: Journal of Crohn's and Colitis

Longitudinal monitoring of disease burden and response using ctDNA from dried blood spots in xenograft models
Authors: C Sauer, K Heider, J Belic, S Boyle, J Hall, D-L Couturier, A An, A Vijayar...
E-pub date: 19 Jan 2022
Journal name:

Publisher Correction: Single-cell mapping of DNA G-quadruplex structures in human cancer cells.
Authors: WWI Hui, A Simeone, KG Zyner, D Tannahill, S Balasubramanian
E-pub date: 12 Jan 2022
Journal name: Sci Rep

Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma-A Proof of Principle Study.
Authors: S Ursprung, R Woitek, MA McLean, AN Priest, M Crispin-Ortuzar, CR Brodie, A...
E-pub date: 11 Jan 2022
Journal name: Cancers (Basel)

Labile Photo-Induced Free Radical in α-Ketoglutaric Acid: a Universal Endogenous Polarizing Agent for In Vivo Hyperpolarized 13 C Magnetic Resonance.
Authors: AP Gaunt, JS Lewis, F Hesse, T Cheng, I Marco-Rius, KM Brindle, A Comment
E-pub date: 10 Jan 2022
Journal name: Angew Chem Int Ed Engl