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Combinatorial CRISPR screen identifies fitness effects of gene paralogues.

Authors: NA Thompson, M Ranzani, L van der Weyden, V Iyer, V Offord, A Droop, F Beha...
E-pub date: 26 Feb 2021
Journal name: Nat Commun

TET2 is a component of the ER complex and controls 5mC to 5hmC conversion at ER cis-regulatory regions

Authors: R broome, I chernukhin, S Jamieson, K Kishore, E Papachristou, S-Q Mao, C G...
E-pub date: 23 Feb 2021
Journal name: Cell Rep

Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB.

Authors: H Holliday, D Roden, S Junankar, SZ Wu, LA Baker, C Krisp, C-L Chan, A McFa...
E-pub date: 19 Feb 2021
Journal name: iScience

Multi-modal imaging of high-risk ductal carcinoma in situ of the breast using C2Am: a targeted cell death imaging agent.

Authors: Z Szucs, J Joseph, TJ Larkin, B Xie, SE Bohndiek, KM Brindle, AA Neves
E-pub date: 17 Feb 2021
Journal name: Breast Cancer Res

Neuron type-specific increase in lamin B1 contributes to nuclear dysfunction in Huntington’s disease.

Authors: R Alcalá-Vida, M Garcia-Forn, C Castany-Pladevall, J Creus-Muncunill, Y It...
E-pub date: 5 Feb 2021
Journal name: EMBO Mol Med

Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila.

Authors: EL Eastwood, KA Jara, S Bornelöv, M Munafò, V Frantzis, E Kneuss, EJ Barb...
E-pub date: 4 Feb 2021
Journal name: Elife

FrenchFISH: Poisson Models for Quantifying DNA Copy Number From Fluorescence In Situ Hybridization of Tissue Sections.

Authors: G Macintyre, AM Piskorz, A Berman, E Ross, DB Morse, K Yuan, D Ennis, JA Pi...
E-pub date: 1 Feb 2021
Journal name: JCO Clin Cancer Inform

Comparative analysis of the AIB1 interactome in breast cancer reveals MTA2 as a repressive partner which silences E-Cadherin to promote EMT and associates with a pro-metastatic phenotype.

Authors: D Varešlija, E Ward, SP Purcell, NS Cosgrove, S Cocchiglia, PJ O'Halloran,...
E-pub date: 1 Feb 2021
Journal name: Oncogene