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Clinical prospects of WRN inhibition as a treatment for MSI tumours.

Authors: DA Morales-Juarez, SP Jackson
E-pub date: 15 Nov 2022
Journal name: NPJ Precis Oncol

Survival Pathways of HIF-Deficient Tumour Cells: TCA Inhibition, Peroxisomal Fatty Acid Oxidation Activation and an AMPK-PGC-1α Hypoxia Sensor.

Authors: MA Golinska, M Stubbs, AL Harris, LG Boros, M Basetti, DJO McIntyre, JR Gri...
E-pub date: 14 Nov 2022
Journal name: Cells

Molecular Subclasses of Clear Cell Ovarian Carcinoma and Their Impact on Disease Behavior and Outcomes.

Authors: KL Bolton, D Chen, R Corona de la Fuente, Z Fu, R Murali, M Köbel, Y Tazi,...
E-pub date: 14 Nov 2022
Journal name: Clin Cancer Res

Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci.

Authors: AA DeVries, J Dennis, JP Tyrer, P-C Peng, SG Coetzee, AL Reyes, JT Plummer,...
E-pub date: 14 Nov 2022
Journal name: J Natl Cancer Inst

Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis.

Authors: D Van Egeren, K Kohli, JL Warner, PL Bedard, G Riely, E Lepisto, D Schrag, ...
E-pub date: 9 Nov 2022
Journal name: Sci Rep

SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling.

Authors: D Sun, O Llora Batlle, J van den Ameele, JC Thomas, P He, K Lim, W Tang, C ...
E-pub date: 2 Nov 2022
Journal name: EMBO J

Deuterium MRSI of tumor cell death in vivo following oral delivery of 2 H-labeled fumarate.

Authors: F Hesse, AJ Wright, F Bulat, V Somai, F Kreis, KM Brindle
E-pub date: 1 Nov 2022
Journal name: Magn Reson Med

Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer

Authors: FC Martins, D-L Couturier, I de Santiago, CM Sauer, M Vias, M Angelova, D S...
E-pub date: 26 Oct 2022
Journal name: Nat Commun