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A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence.
Authors: JS Carroll, OW Prall, EA Musgrove, RL Sutherland
E-pub date: 8 Dec 2000
Journal name: J Biol Chem

Expression of Ku70 correlates with survival in carcinoma of the cervix.
Authors: CR Wilson, SE Davidson, GP Margison, SP Jackson, JH Hendry, CM West
E-pub date: 1 Dec 2000
Journal name: Br J Cancer

The science of chemical discovery: probing the unknown with new technologies.
Authors: S Balasubramanian
E-pub date: 1 Dec 2000
Journal name: Drug Discov Today

LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae.
Authors: J Rouse, SP Jackson
E-pub date: 1 Nov 2000
Journal name: EMBO J

Mechanism of autoregulation by an archaeal transcriptional repressor.
Authors: SD Bell, SP Jackson
E-pub date: 13 Oct 2000
Journal name: J Biol Chem

Erratum: BcL-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC (Nature (1999) 399 (438-487))
Authors: S Shimizu, M Narita, Y Tsujimoto
E-pub date: 1 Oct 2000
Journal name: Nature

A new X-ray sensitive CHO cell mutant of ionizing radiation group 7,XR-C2, that is defective in DSB repair but has only a mild defect in V(D)J recombination.
Authors: A Errami, WJ Overkamp, DM He, AA Friedl, DA Gell, F Eckardt-Schupp, SP Jack...
E-pub date: 15 Sep 2000
Journal name: Mutat Res

Charting a course through RNA polymerase.
Authors: SD Bell, SP Jackson
E-pub date: 1 Sep 2000
Journal name: Nat Struct Biol