Publications

Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma.

Authors: J Obacz, JA Valer, R Nibhani, TS Adams, JC Schupp, N Veale, A Lewis-Wade, J...

E-pub date: 1 Jan 2024

Journal name: Eur Respir J

The dCMP deaminase DCTD and the E3 ligase TOPORS are central mediators of decitabine cytotoxicity

Authors: CJ Carnie, MJ Götz, CS Palma-Chaundler, P Weickert, AR Wanders, A Serrano-...

E-pub date: 23 Dec 2023

Journal name:

RAD54L2 counters TOP2-DNA adducts to promote genome stability.

Authors: G D'Alessandro, DA Morales-Juarez, SL Richards, KC Nitiss, A Serrano-Benite...

E-pub date: 8 Dec 2023

Journal name: Sci Adv

Deep learning-based segmentation of multisite disease in ovarian cancer.

Authors: T Buddenkotte, L Rundo, R Woitek, L Escudero Sanchez, L Beer, M Crispin-Ort...

E-pub date: 7 Dec 2023

Journal name: Eur Radiol Exp

KCNQ potassium channels modulate Wnt activity in gastro-oesophageal adenocarcinomas.

Authors: D Shorthouse, L Zhuang, EP Rahrmann, C Kosmidou, K Wickham Rahrmann, M Hall...

E-pub date: 1 Dec 2023

Journal name: Life Sci Alliance

Omentum-derived matrix enables the study of metastatic ovarian cancer and stromal cell functions in a physiologically relevant environment.

Authors: LJ Neilson, D Cartwright, M Risteli, EM Jokinen, L McGarry, T Sandvik, K Ni...

E-pub date: 1 Dec 2023

Journal name: Matrix Biol Plus

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus

Authors: J van Lopik, A Alizada, M-A Trapotsi, GJ Hannon, S Bornelöv, B Czech Nicho...

E-pub date: 13 Nov 2023

Journal name: Nat Commun

Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson’s disease mouse model.

Authors: T-SZ Fang, Y Sun, AC Pearce, S Eleuteri, M Kemp, CA Luckhurst, R Williams, ...

E-pub date: 13 Nov 2023

Journal name: Nature Communications

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Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma.

The dCMP deaminase DCTD and the E3 ligase TOPORS are central mediators of decitabine cytotoxicity

RAD54L2 counters TOP2-DNA adducts to promote genome stability.

Deep learning-based segmentation of multisite disease in ovarian cancer.

KCNQ potassium channels modulate Wnt activity in gastro-oesophageal adenocarcinomas.

Omentum-derived matrix enables the study of metastatic ovarian cancer and stromal cell functions in a physiologically relevant environment.

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus

Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson’s disease mouse model.

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Research Groups

Core Facilities

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End date

Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma.

The dCMP deaminase DCTD and the E3 ligase TOPORS are central mediators of decitabine cytotoxicity

RAD54L2 counters TOP2-DNA adducts to promote genome stability.

Deep learning-based segmentation of multisite disease in ovarian cancer.

KCNQ potassium channels modulate Wnt activity in gastro-oesophageal adenocarcinomas.

Omentum-derived matrix enables the study of metastatic ovarian cancer and stromal cell functions in a physiologically relevant environment.

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus

Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson’s disease mouse model.