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miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex.
Authors: D De Pietri Tonelli, JN Pulvers, C Haffner, EP Murchison, GJ Hannon, WB Hut...
Research group: Hannon Group
E-pub date: 1 Dec 2008
Journal name: Development

Global analysis of the medulloblastoma epigenome identifies disease-subgroup-specific inactivation of COL1A2.
Authors: JA Anderton, JC Lindsey, ME Lusher, RJ Gilbertson, S Bailey, DW Ellison, SC...
Research group: Gilbertson Group
E-pub date: 1 Dec 2008
Journal name: Neuro Oncol

Metamodel-based generation of WSRF-compliant SOA for collaborative cancer research
Authors: T Zang, R Calinescu, S Harris, A Tsui, C Crichton, M Kwiatkowska, J Gibbons...
Research group: Brenton Group
E-pub date: 1 Dec 2008
Journal name: Proceedings 4th IEEE International Conference on Escience Escience 2008

An epigenetic role for maternally inherited piRNAs in transposon silencing.
Authors: J Brennecke, CD Malone, AA Aravin, R Sachidanandam, A Stark, GJ Hannon
Research group: Hannon Group
E-pub date: 28 Nov 2008
Journal name: Science

An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer.
Authors: L Zender, W Xue, J Zuber, CP Semighini, A Krasnitz, B Ma, P Zender, S Kubic...
Research group: Hannon Group
E-pub date: 28 Nov 2008
Journal name: Cell

Diarylethynyl amides that recognize the parallel conformation of genomic promoter DNA G-quadruplexes.
Authors: J Dash, PS Shirude, S-TD Hsu, S Balasubramanian
Research group: Balasubramanian Group
E-pub date: 26 Nov 2008
Journal name: J Am Chem Soc

A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres.
Authors: R Rodriguez, S Müller, JA Yeoman, C Trentesaux, J-F Riou, S Balasubramania...
Research group: Balasubramanian Group
E-pub date: 26 Nov 2008
Journal name: J Am Chem Soc

Using chemical probes to investigate the sub-inhibitory effects of azithromycin.
Authors: FG Glansdorp, RJ Spandl, JE Swatton, O Loiseleur, M Welch, DR Spring
Research group: Research instrumentation and cell services
E-pub date: 21 Nov 2008
Journal name: Org Biomol Chem