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Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer.

Authors: L Ying, JJ Green, H Li, D Klenerman, S Balasubramanian
E-pub date: 9 Dec 2003
Journal name: Proc Natl Acad Sci U S A

Free energy lights the path toward more effective RNAi.

Authors: JM Silva, R Sachidanandam, GJ Hannon
E-pub date: 1 Dec 2003
Journal name: Nat Genet

The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes.

Authors: J-J Song, J Liu, NH Tolia, J Schneiderman, SK Smith, RA Martienssen, GJ Han...
E-pub date: 1 Dec 2003
Journal name: Nat Struct Biol

A proton-fuelled DNA nanomachine.

Authors: D Liu, S Balasubramanian
E-pub date: 1 Dec 2003
Journal name: Angew Chem Int Ed Engl

Identification of a new RNA.RNA interaction site for human telomerase RNA (hTR): structural implications for hTR accumulation and a dyskeratosis congenita point mutation.

Authors: X Ren, G Gavory, H Li, L Ying, D Klenerman, S Balasubramanian
E-pub date: 15 Nov 2003
Journal name: Nucleic Acids Res

A DNA damage checkpoint response in telomere-initiated senescence.

Authors: F d'Adda di Fagagna, PM Reaper, L Clay-Farrace, H Fiegler, P Carr, T Von Zg...
E-pub date: 13 Nov 2003
Journal name: Nature

PDGFRB is overexpressed in metastatic medulloblastoma.

Authors: RJ Gilbertson, SC Clifford
E-pub date: 1 Nov 2003
Journal name: Nat Genet

Dicer is essential for mouse development.

Authors: E Bernstein, SY Kim, MA Carmell, EP Murchison, H Alcorn, MZ Li, AA Mills, S...
E-pub date: 1 Nov 2003
Journal name: Nat Genet