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A-ring dihalogenation increases the cellular activity of combretastatin-templated tetrazoles.
Authors: TM Beale, DM Allwood, A Bender, PJ Bond, JD Brenton, DS Charnock-Jones, SV ...
Research group: Brenton Group
E-pub date: 8 Mar 2012
Journal name: ACS Med Chem Lett

Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling.
Authors: VWY Wong, DE Stange, ME Page, S Buczacki, A Wabik, S Itami, M van de Weteri...
Research group: Winton Group
E-pub date: 4 Mar 2012
Journal name: Nat Cell Biol

Production of transgenic calves expressing an shRNA targeting myostatin.
Authors: K Tessanne, MC Golding, CR Long, MD Peoples, G Hannon, ME Westhusin
Research group: Hannon Group
E-pub date: 1 Mar 2012
Journal name: Mol Reprod Dev

Cancer cell senescence: a new frontier in drug development.
Authors: CJ Cairney, AE Bilsland, TRJ Evans, J Roffey, DC Bennett, M Narita, CJ Torr...
Research group: Narita Group
E-pub date: 1 Mar 2012
Journal name: Drug Discov Today

The brain tumor microenvironment.
Authors: NA Charles, EC Holland, R Gilbertson, R Glass, H Kettenmann
Research group: Gilbertson Group
E-pub date: 1 Mar 2012
Journal name: Glia

Increased endothelial cell selectivity of triazole-bridged dihalogenated A-ring analogues of combretastatin A-1.
Authors: TM Beale, PJ Bond, JD Brenton, DS Charnock-Jones, SV Ley, RM Myers
Research group: Brenton Group
E-pub date: 1 Mar 2012
Journal name: Bioorganic and Medicinal Chemistry

Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair.
Authors: SE Polo, AN Blackford, JR Chapman, L Baskcomb, S Gravel, A Rusch, A Thomas,...
Research group: Jackson Group
E-pub date: 24 Feb 2012
Journal name: Mol Cell

Transducin-like enhancer protein 1 mediates estrogen receptor binding and transcriptional activity in breast cancer cells.
Authors: KA Holmes, A Hurtado, GD Brown, R Launchbury, CS Ross-Innes, J Hadfield, DT...
Research group: Carroll Group
E-pub date: 21 Feb 2012
Journal name: Proceedings of the National Academy of Sciences of the United States of America