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CtIP-mediated resection is essential for viability and can operate independently of BRCA1.
Authors: F Polato, E Callen, N Wong, R Faryabi, S Bunting, H-T Chen, M Kozak, MJ Kru...
Research group: Jackson Group
E-pub date: 2 Jun 2014
Journal name: J Exp Med

The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex.
Authors: Z Ji, H Mohammed, A Webber, J Ridsdale, N Han, JS Carroll, AD Sharrocks
Research group: Carroll Group
E-pub date: 1 Jun 2014
Journal name: Nucleic Acids Res

OC-016 The Toll-like Receptor Pathway Is Recurrently Mutated In Oesophageal Adenocarcinoma
Authors: F Elliott, C Ross-Innes, Eldridge, R Fitzgerald
Research group: Bioinformatics
E-pub date: 1 Jun 2014
Journal name: Gut

PTU-153 The Timing Of Oncogenic Events In The Evolution Of The Oesophageal Adenocarcinoma Genome And Implications For Clinical Diagnostics.
Authors: J Weaver, C Ross-Innes, N Shannon, A Lynch, M Murtaza, T Forshew, M Dunning...
Research group: Bioinformatics,
E-pub date: 1 Jun 2014
Journal name: Gut

USP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism.
Authors: PA Knobel, R Belotserkovskaya, Y Galanty, CK Schmidt, SP Jackson, TH Strack...
Research group: Jackson Group
E-pub date: 1 Jun 2014
Journal name: Mol Cell Biol

Addendum: Quantitative sequencing of 5-formylcytosine in DNA at single-base resolution.
Authors: MJ Booth, G Marsico, M Bachman, D Beraldi, S Balasubramanian
Research group: Balasubramanian Group
E-pub date: 21 May 2014
Journal name: Nat Chem

ARIEL 2/3: An integrated clinical trial program to assess activity of rucaparib in ovarian cancer and to identify tumor molecular characteristics predictive of response.
Authors: EM Swisher, IA McNeish, RL Coleman, J Brenton, SH Kaufmann, AR Allen, M Rap...
Research group: Brenton Group
E-pub date: 20 May 2014
Journal name: Journal of Clinical Oncology

A national platform for molecular diagnostics: Results of the Cancer Research U.K. Stratified Medicine Programme.
Authors: E Shaw, R Butler, D Gonzalez de Castro, M Griffiths, A Hanby, J Hair, F Rae...
Research group: Brenton Group
E-pub date: 20 May 2014
Journal name: Journal of Clinical Oncology