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The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex.

Authors: Z Ji, H Mohammed, A Webber, J Ridsdale, N Han, JS Carroll, AD Sharrocks
E-pub date: 1 Jun 2014
Journal name: Nucleic Acids Res

THE TOLL-LIKE RECEPTOR PATHWAY IS RECURRENTLY MUTATED IN OESOPHAGEAL ADENOCARCINOMA

Authors: DRF Elliott, CS Ross-Innes, MD Eldridge, RC Fitzgerald
E-pub date: 1 Jun 2014
Journal name: Gut

PTU-153 The Timing Of Oncogenic Events In The Evolution Of The Oesophageal Adenocarcinoma Genome And Implications For Clinical Diagnostics.

Authors: J Weaver, C Ross-Innes, N Shannon, A Lynch, M Murtaza, T Forshew, M Dunning...
E-pub date: 1 Jun 2014
Journal name: Gut

USP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism.

Authors: PA Knobel, R Belotserkovskaya, Y Galanty, CK Schmidt, SP Jackson, TH Strack...
E-pub date: 1 Jun 2014
Journal name: Mol Cell Biol

Addendum: Quantitative sequencing of 5-formylcytosine in DNA at single-base resolution.

Authors: MJ Booth, G Marsico, M Bachman, D Beraldi, S Balasubramanian
E-pub date: 21 May 2014
Journal name: Nat Chem

ARIEL 2/3: An integrated clinical trial program to assess activity of rucaparib in ovarian cancer and to identify tumor molecular characteristics predictive of response.

Authors: EM Swisher, IA McNeish, RL Coleman, J Brenton, SH Kaufmann, AR Allen, M Rap...
E-pub date: 20 May 2014
Journal name: Journal of Clinical Oncology

A national platform for molecular diagnostics: Results of the Cancer Research UK Stratified Medicine Programme

Authors: E Shaw, R Butler, DG de Castro, M Griffiths, A Hanby, J Hair, F Rae, J Roga...
E-pub date: 20 May 2014
Journal name: Journal of Clinical Oncology

ICON8: An international randomized trial comparing two dose dense regimens, 3-weekly carboplatin plus weekly paclitaxel (CwT), and weekly carhoplatin-paclitaxel (wCwT), to standard 3-weekly treatment in women with newly diagnosed ovarian, fallopian tube, and primary peritoneal cancer

Authors: J Hook, SP Stenning, J Brenton, SB Kaye, IA McNeish, R Naik, T Perron, J Pe...
E-pub date: 20 May 2014
Journal name: Journal of Clinical Oncology