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Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

Authors: JS Brown, N Lukashchuk, M Sczaniecka-Clift, S Britton, C le Sage, P Calsou,...
E-pub date: 5 May 2015
Journal name: Cell Rep

Preclinical examination of clofarabine in pediatric ependymoma: intratumoral concentrations insufficient to warrant further study.

Authors: YT Patel, MO Jacus, N Boulos, JD Dapper, AD Davis, PK Vuppala, BB Freeman, ...
E-pub date: 1 May 2015
Journal name: Cancer Chemother Pharmacol

An open-label, two-stage, phase II study of bevacizumab and lapatinib in children with recurrent or refractory ependymoma: a collaborative ependymoma research network study (CERN).

Authors: M DeWire, M Fouladi, DC Turner, C Wetmore, C Hawkins, C Jacobs, Y Yuan, D L...
E-pub date: 1 May 2015
Journal name: J Neurooncol

ATP synthase promotes germ cell differentiation independent of oxidative phosphorylation.

Authors: FK Teixeira, CG Sanchez, TR Hurd, JRK Seifert, B Czech, JB Preall, GJ Hanno...
E-pub date: 1 May 2015
Journal name: Nat Cell Biol

(13) C magnetic resonance spectroscopic imaging of hyperpolarized [1-(13) C, U-(2) H5 ] ethanol oxidation can be used to assess aldehyde dehydrogenase activity in vivo.

Authors: P Dzien, MI Kettunen, I Marco-Rius, EM Serrao, TB Rodrigues, TJ Larkin, KN ...
E-pub date: 1 May 2015
Journal name: Magn Reson Med

A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis.

Authors: E Wagenblast, M Soto, S Gutiérrez-Ángel, CA Hartl, AL Gable, AR Maceli, N...
E-pub date: 16 Apr 2015
Journal name: Nature

Paclitaxel resistance increases oncolytic adenovirus efficacy via upregulated CAR expression and dysfunctional cell cycle control.

Authors: CK Ingemarsdotter, LA Tookman, A Browne, K Pirlo, R Cutts, C Chelela, KF Kh...
E-pub date: 1 Apr 2015
Journal name: Mol Oncol

Transcription factors and chromatin proteins as therapeutic targets in cancer.

Authors: SJ Johnston, JS Carroll
E-pub date: 1 Apr 2015
Journal name: Biochim Biophys Acta