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Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson’s disease mouse model.

Authors: T-SZ Fang, Y Sun, AC Pearce, S Eleuteri, M Kemp, CA Luckhurst, R Williams, ...
E-pub date: 13 Nov 2023
Journal name: Nature Communications

Concurrent RB1 loss and BRCA-deficiency predicts enhanced immunological response and long-term survival in tubo-ovarian high-grade serous carcinoma.

Authors: FAM Saner, K Takahashi, T Budden, A Pandey, D Ariyaratne, TA Zwimpfer, NS M...
E-pub date: 10 Nov 2023
Journal name:

MO71-1 Systematic quantification of ovarian tumour heterogeneity using an in silico tissue microarray approach

Authors: M Reinius, A Crombé, T Bradley, R Barker-Clarke, M Crispin-Ortuzar, JD Bre...
E-pub date: 1 Nov 2023
Journal name: Annals of Oncology

Integrated radiogenomics models predict response to neoadjuvant chemotherapy in high grade serous ovarian cancer

Authors: M Crispin-Ortuzar, R Woitek, MAV Reinius, E Moore, L Beer, V Bura, L Rundo,...
E-pub date: 24 Oct 2023
Journal name: Nat Commun

Dual-modality imaging of immunofluorescence and imaging mass cytometry for whole-slide imaging and accurate segmentation.

Authors: EN Kim, PZ Chen, D Bressan, M Tripathi, A Miremadi, M di Pietro, LM Coussen...
E-pub date: 23 Oct 2023
Journal name: Cell Rep Methods

Molecular landscape and functional characterization of centrosome amplification in ovarian cancer.

Authors: CM Sauer, JA Hall, D-L Couturier, T Bradley, AM Piskorz, J Griffiths, A Saw...
E-pub date: 16 Oct 2023
Journal name: Nat Commun

Pan-cancer evolution signatures link clonal expansion to dynamic changes in the tumour immune microenvironment

Authors: X Yang, W Liu, G Macintyre, P Van Loo, F Markowetz, P Bailey, K Yuan
E-pub date: 13 Oct 2023
Journal name:

Cancers make their own luck: theories of cancer origins.

Authors: A Jassim, EP Rahrmann, BD Simons, RJ Gilbertson
E-pub date: 1 Oct 2023
Journal name: Nat Rev Cancer