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Data from Visualizing Cancer Heterogeneity at the Molecular and Cellular Levels: Lessons from Rosetta

Authors: RJA Goodwin, JF Marshall, G Poulogiannis, M Yuneva, KM Brindle, Z Takáts, ...
E-pub date: 13 Jan 2025
Journal name:

Predicting Personalised Therapeutic Combinations in Non-Small Cell Lung Cancer Using In Silico Modelling

Authors: MA Clarke, CG Barker, A Nicholls, MP Handler, L Pickard, A Shah, D Walter, ...
E-pub date: 12 Jan 2025
Journal name:

TDP1 splice-site mutation causes HAP1 cell hypersensitivity to topoisomerase I inhibition

Authors: CG Goh, A Bader, T-A Tran, R Belotserkovskaya, G D'Alessandro, S Jackson
E-pub date: 11 Jan 2025
Journal name: Nucleic Acids Research

KLF5 loss sensitizes cells to ATR inhibition and is synthetic lethal with ARID1A deficiency.

Authors: SW Awwad, C Doyle, J Coulthard, AS Bader, N Gueorguieva, S Lam, V Gupta, R ...
E-pub date: 8 Jan 2025
Journal name: Nature Communications

Selective Photocatalytic C-H Oxidation of 5-Methylcytosine in DNA.

Authors: T Yan, Y Chen, B Mortishire-Smith, A Simeone, A Hofer, S Balasubramanian
E-pub date: 2 Jan 2025
Journal name: Angew Chem Int Ed Engl

Insights from the bottom-up development of LGR5-targeting immunotherapeutics.

Authors: N Mueller, MA de la Roche, M de la Roche
E-pub date: 30 Dec 2024
Journal name: Immunotherapy Advances

The EstroGene2.0 database for endocrine therapy response and resistance in breast cancer.

Authors: Z Li, F Chen, L Chen, J Liu, D Tseng, F Hadi, S Omarjee, K Kishore, J Kent,...
E-pub date: 19 Dec 2024
Journal name: NPJ Breast Cancer

Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer

Authors: L Veghini, D Pasini, R Fang, P Delfino, D Filippini, C Neander, C Vicentini...
E-pub date: 3 Dec 2024
Journal name: Nat Commun