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ZFTA-RELA ependymomas make itaconate to epigenetically drive fusion expression.
Authors: SK Natarajan, J Lum, JH Skeans, M Nenwani, S Eyunni, M Mota, JM Bayliss, A ...
E-pub date: 4 Feb 2026
Journal name: Nature
ApCAFs: spatial niches and therapeutic insights across cancers.
Authors: W Li, G Nsubuga, G Biffi
E-pub date: 1 Feb 2026
Journal name: Trends Cancer
Treatment resistance to platinum-based chemotherapy in lung and ovarian cancer is driven by a targetable TGFβ senescent secretome.
Authors:
E-pub date: 1 Feb 2026
Journal name: Nat Aging
Loss of CTLH component MAEA impairs DNA repair and replication and leads to developmental delay.
Authors: SH Hough, SS Jhujh, SW Awwad, OE Lewis, S Lam, JC Thomas, T Mosler, A Bader...
E-pub date: 1 Feb 2026
Journal name: EMBO Mol Med
MDC1 counteracts replication fork reversal and mediates chemosensitivity in BRCA1/2-deficient tumors.
Authors: H Dogan, M Liptay, JS Barbosa, E Gogola, AA Duarte, JA Schmid, I Klebic, M ...
E-pub date: 1 Feb 2026
Journal name: Oncogene
Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.
Authors: M Rossi, P Altea-Manzano, M Demicco, G Doglioni, L Bornes, M Fukano, A Vand...
E-pub date: 1 Feb 2026
Journal name: Nature
Childhood brain tumors instruct cranial hematopoiesis and immunotolerance.
Authors: E Cooper, DA Posner, CYC Lee, L Hu, S Bonner, JT Taylor, O Baldwin, R Jimen...
E-pub date: 1 Feb 2026
Journal name: Nat Genet
ICON8B: GCIG phase III randomised trial comparing first-line weekly dose-dense chemotherapy + bevacizumab to three-weekly chemotherapy + bevacizumab in high-risk stage III-IV epithelial ovarian cancer: final overall survival (OS) analysis
Authors: A Clamp, I Mcneish, D Radice, R Lord, A Michael, A Cook, R Agarwal, A Walth...
E-pub date: 1 Feb 2026
Journal name: International Journal of Gynecological Cancer