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Molecular pathogenesis of ovarian clear cell carcinoma.
Authors: I Gounaris, JD Brenton
E-pub date: 1 Aug 2015
Journal name: Future Oncol

EUTROC PiSARRO: A phase Ib study combining APR-246 with standard chemotherapy in platinum sensitive relapsed high grade serous ovarian carcinoma (HGSOC).
Authors: C Gourley, H Gabra, I Vergote, B Basu, J Brenton, M Von Euler, U Bjoerklund...
E-pub date: 1 Aug 2015
Journal name: JOURNAL OF CLINICAL ONCOLOGY

A randomized, placebo-controlled phase II trial comparing gemcitabine monotherapy to gemcitabine in combination with AZD 1775 (MK 1775) in women with recurrent, platinum-resistant epithelial ovarian, primary peritoneal, or Fallopian tube cancers: Trial of Princess Margaret, Mayo, Chicago, and California consortia.
Authors: S Lheureux, JI Weberpals, AEW Hendrickson, GF Fleming, A Olawaiye, I Brana,...
E-pub date: 1 Aug 2015
Journal name: JOURNAL OF CLINICAL ONCOLOGY

Final results of ARIEL2 (Part 1): A phase 2 trial to prospectively identify ovarian cancer (OC) responders to rucaparib using tumor genetic analysis
Authors: R Kristeleit, E Swisher, A Oza, RL Coleman, C Scott, G Konecny, A Tinker, D...
E-pub date: 1 Aug 2015
Journal name: EUROPEAN JOURNAL OF CANCER

Assessment of clinical applications of circulating tumor DNA using an enhanced TAm-Seq platform
Authors: ARJ Lawson, V Plagno, A Fahem, T Forshew, JD Brenton, D Gale, N Rosenfeld
E-pub date: 1 Aug 2015
Journal name: CANCER RESEARCH

Preliminary results from PiSARRO, a phase Ib/II study of APR-246, a mutant p53 reactivating small molecule, in combination with standard chemotherapy in platinum-sensitive ovarian cancer
Authors: M von Euler, KG Wiman, H Gabra, JD Brenton, B Basu, I Vergote, C Gourley, A...
E-pub date: 1 Aug 2015
Journal name: CANCER RESEARCH

Genomic Applications in Epithelial Ovarian Malignancies
Authors: JD Brenton
E-pub date: 1 Aug 2015
Journal name:

Genome wide analysis of AR-cell cycle interplay reveals novel functions in cancer
Authors: C McNair, J Goodwin, M Augello, A Urbanucci, M Schiewer, C Comstock, A Erte...
E-pub date: 1 Aug 2015
Journal name: CANCER RESEARCH