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Cross-species graph-embedding unmasks the ageing microenvironment as a key determinant of pancreatic cancer malignant cell biology and therapy response
Authors: JA Henríquez, M Jihad, A Jassim, EG Lloyd, W Luo, JS Manansala, S Harish, ...
Research group: Biffi Group
E-pub date: 5 Feb 2026
Journal name:
MMP-cleavable linker platform for tumour-responsive homo- and heterobivalent antibody-drug conjugates.
Authors: AJ Counsell, SJ Walsh, N Ashman, M Park, FM Dannheim, TA King, T Wharton, J...
Research group: Carroll Group
E-pub date: 4 Feb 2026
Journal name: Chem Sci
Childhood brain tumors instruct cranial hematopoiesis and immunotolerance.
Authors: E Cooper, DA Posner, CYC Lee, L Hu, S Bonner, JT Taylor, O Baldwin, R Jimen...
Research group: Proteomics, Gilbertson Group, Mair Group, Halim Group
E-pub date: 1 Feb 2026
Journal name: Nat Genet
ApCAFs: spatial niches and therapeutic insights across cancers.
Authors: W Li, G Nsubuga, G Biffi
Research group: Biffi Group
E-pub date: 1 Feb 2026
Journal name: Trends Cancer
Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.
Authors: M Rossi, P Altea-Manzano, M Demicco, G Doglioni, L Bornes, M Fukano, A Vand...
Research group: Hannon Group
E-pub date: 1 Feb 2026
Journal name: Nature
Treatment resistance to platinum-based chemotherapy in lung and ovarian cancer is driven by a targetable TGFβ senescent secretome.
Authors:
Research group: Brenton Group, Narita Group
E-pub date: 1 Feb 2026
Journal name: Nat Aging
ICON8B: GCIG phase III randomised trial comparing first-line weekly dose-dense chemotherapy + bevacizumab to three-weekly chemotherapy + bevacizumab in high-risk stage III-IV epithelial ovarian cancer: final overall survival (OS) analysis
Authors: A Clamp, I Mcneish, D Radice, R Lord, A Michael, A Cook, R Agarwal, A Walth...
Research group: Brenton Group
E-pub date: 1 Feb 2026
Journal name: International Journal of Gynecological Cancer
Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism
Authors: AM Vaquié, DR Shah, EES Brechbühl, M McNicholas, Z Xu, JH Stockley, L Mor...
Research group:
E-pub date: 1 Feb 2026
Journal name: Mol Oncol