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ThX – a next-generation probe for the early detection of amyloid aggregates.
Authors: L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe...
Research group: Bohndiek Group
E-pub date: 21 Feb 2020
Journal name: Chem Sci

AZD4573 Is a Highly Selective CDK9 Inhibitor That Suppresses MCL-1 and Induces Apoptosis in Hematologic Cancer Cells.
Authors: J Cidado, S Boiko, T Proia, D Ferguson, SW Criscione, M San Martin, P Pop-D...
Research group: Proteomics
E-pub date: 15 Feb 2020
Journal name: Clin Cancer Res

Abstract P6-04-18: The regulatory role of activating transcription factor-2 (ATF2) in modulating tamoxifen resistance in estrogen-receptor positive breast cancer
Authors: A Giannoudis, MI Malki, H Mohammed, B Rudraraju, S Menon, S Ali, JS Carroll...
Research group: Carroll Group
E-pub date: 15 Feb 2020
Journal name: Cancer Research

Abstract GS2-03: The androgen receptor is a tumour suppressor in estrogen receptor positive breast cancer
Authors: E Lim, TA Hickey, LA Selth, KM Chia, HH Milioli, D Roden, G Laven-Law, S Ji...
Research group: Carroll Group
E-pub date: 15 Feb 2020
Journal name: Cancer Research

Abstract P6-05-02: Estrogen receptor beta repurposes EZH2 to inhibit oncogenic NFκB signaling in triple negative breast cancer
Authors: KG Aspros, AW Nelson, Z Ye, Z Sun, I Chernukhin, JS Carroll, JN Ingle, MP G...
Research group: Carroll Group
E-pub date: 15 Feb 2020
Journal name: Cancer Research

PIK3R1W624R Is an Actionable Mutation in High Grade Serous Ovarian Carcinoma.
Authors: C D'Ambrosio, J Erriquez, M Arigoni, S Capellero, G Mittica, E Ghisoni, F B...
Research group: Brenton Group
E-pub date: 14 Feb 2020
Journal name: Cells

PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1.
Authors: R Belotserkovskaya, E Raga Gil, N Lawrence, R Butler, G Clifford, MD Wilson...
Research group: Jackson Group
E-pub date: 10 Feb 2020
Journal name: Nat Commun

Chronic irradiation of human cells reduces histone levels and deregulates gene expression.
Authors: DJ Lowe, M Herzog, T Mosler, H Cohen, S Felton, P Beli, K Raj, Y Galanty, S...
Research group: Jackson Group
E-pub date: 10 Feb 2020
Journal name: Sci Rep