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Estrogen receptor beta repurposes EZH2 to inhibit oncogenic NFÎşB signaling in triple negative breast cancer

Authors: KGM Aspros, AW Nelson, Z Ye, Z Sun, I Chernukhin, JS Carroll, JN Ingle, MP ...
E-pub date: 15 Feb 2020
Journal name: Cancer Research

PIK3R1W624R Is an Actionable Mutation in High Grade Serous Ovarian Carcinoma.

Authors: C D'Ambrosio, J Erriquez, M Arigoni, S Capellero, G Mittica, E Ghisoni, F B...
E-pub date: 14 Feb 2020
Journal name: Cells

PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1.

Authors: R Belotserkovskaya, E Raga Gil, N Lawrence, R Butler, G Clifford, MD Wilson...
E-pub date: 10 Feb 2020
Journal name: Nat Commun

Chronic irradiation of human cells reduces histone levels and deregulates gene expression.

Authors: DJ Lowe, M Herzog, T Mosler, H Cohen, S Felton, P Beli, K Raj, Y Galanty, S...
E-pub date: 10 Feb 2020
Journal name: Sci Rep

Inferring structural variant cancer cell fraction.

Authors: M Cmero, K Yuan, CS Ong, J Schröder, PCAWG Evolution and Heterogeneity Wo...
E-pub date: 5 Feb 2020
Journal name: Nat Commun

Total synthesis and biological evaluation of simplified aplyronine analogues as synthetically tractable anticancer agents.

Authors: TR Pettigrew, RJ Porter, SJ Walsh, MP Housden, NYS Lam, JS Carroll, JS Park...
E-pub date: 4 Feb 2020
Journal name: Chem Commun (Camb)

A Spontaneous Ring-Opening Reaction Leads to a Repair-Resistant Thymine Oxidation Product in Genomic DNA.

Authors: AB Sahakyan, A Mahtey, F Kawasaki, S Balasubramanian
E-pub date: 3 Feb 2020
Journal name: Chembiochem

The evolutionary history of 2,658 cancers.

Authors: M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, TJ M...
E-pub date: 1 Feb 2020
Journal name: Nature