miR-34a sets the “sweet spot” for notch in colorectal cancer stem cells.
- Abstract:
- Mechanisms underlying alternative modes of symmetric versus asymmetric stem cell fates are not well understood. In this issue of Cell Stem Cell, Bu et al. (2013) find that miR-34a acts as a toggle switch for Notch signaling that dictates binary symmetric and asymmetric fates in colon cancer stem cells.
- Authors:
- DJ Winton
- Journal:
- Cell Stem Cell
- Citation info:
- 12(5):499-501
- Publication date:
- 2nd May 2013
- Full text
- DOI