Mechanochemical properties of individual human telomeric RNA (TERRA) G-quadruplexes.

Abstract:

Potential functions: By following the unfolding and refolding of individual human RNA telomeric (TERRA) G-quadruplexes (GQs) in laser tweezers, the mechanical stability and transition kinetics of RNA GQs are obtained. Comparison between TERRA and DNA GQs suggests their different regulatory capacities for processes associated with human telomeres.

Authors:

PM Yangyuoru, AYQ Zhang, Z Shi, D Koirala, S Balasubramanian, H Mao

Journal:

Chembiochem

Citation info:

14(15):1931-1935

Publication date:

11th Oct 2013

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