Measurements of the growth and distribution of mammalian cells in a hollow-fiber bioreactor using nuclear magnetic resonance imaging.
- Abstract:
- We have used diffusion-weighted 1H NMR micro-imaging and localized spectroscopy techniques to monitor the growth and distribution of mammalian cells in a hollow-fiber bioreactor. Non-invasive NMR measurements of this type should also allow investigation of metabolic heterogeneity and assist in future designs of hollow-fiber systems.
- Authors:
- R Callies, ME Jackson, KM Brindle
- Journal:
- Biotechnology (N Y)
- Citation info:
- 12(1):75-78
- Publication date:
- 1st Jan 1994
- Full text
- DOI