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Histological predictors of outcome in ependymoma are dependent on anatomic site within the central nervous system.

Abstract:
Ependymomas originate in posterior fossa (PF), supratentorial (ST) or spinal cord (SC) compartments. At present, grading schemes are applied independent of anatomic site. We performed detailed histological examination on 238 World Health Organization grade II and III ependymomas. Among PF ependymomas, the presence of hypercellular areas, necrosis, microvascular proliferation and elevated mitotic rate (all P 
Authors:
A Raghunathan, K Wani, TS Armstrong, E Vera-Bolanos, M Fouladi, R Gilbertson, A Gajjar, S Goldman, NL Lehman, P Metellus, T Mikkelsen, MJT Necesito-Reyes, A Omuro, RJ Packer, S Partap, IF Pollack, MD Prados, HI Robins, R Soffietti, J Wu, CR Miller, MR Gilbert, KD Aldape, Collaborative Ependymoma Research Network
Journal:
Brain Pathol
Citation info:
23(5):584-594
Publication date:
1st Sep 2013
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