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Ensemble and single molecule FRET analysis of the structure and unfolding kinetics of the c-kit promoter quadruplexes.

Abstract:
FRET analysis has been used to examine the folded conformations and differing kinetic stabilities of two DNA G-quadruplexes (c-kit 1 and c-kit 2) derived from sequences found in the promoter of the c-kit proto-oncogene.
Authors:
A Fegan, PS Shirude, L Ying, S Balasubramanian
Journal:
Chem Commun (Camb)
Citation info:
46(6):946-948
Publication date:
14th Feb 2010
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