Building Three-Dimensional Surface Biological Assemblies on the Nanometer Scale

Abstract:

We describe a new approach for building 3D protein−DNA complex features on patterned surfaces created by microcontact printing and AFM nanoshaving using the sequential assembly of streptavidin and bis-biotinylated DNA. We demonstrate that this approach offers fine control over the feature position, size, and especially height, where we have nanometer precision.

Authors:

Zhou, A Bruckbauer, Ying, C Abell, D Klenerman

Journal:

Nano Letters

Citation info:

3(11):1517-1520

Publication date:

1st Nov 2003

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