A saltationist theory of cancer evolution.

Abstract:

A new study based on single-nucleus sequencing reports that triple-negative breast cancers acquire copy number aberrations in short punctuated bursts in the earliest stages of tumor evolution, rather than continuously and gradually, challenging prevailing models of tumor evolution.

Authors:

F Markowetz

Journal:

Nat Genet

Citation info:

48(10):1102-1103

Publication date:

28th Sep 2016

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